Research Roundup

The Distinctive Psychopathology of NMDAR-antibody Encephalitis Compared with Primary Psychoses: An International, Multicentre, Retrospective Phenotypic Analysis

Effect of Anti-Inflammatory Treatment on Depressive Symptom Severity and Anhedonia in Depressed Individuals With Elevated Inflammation: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Neuropsychiatric Associations of Mast Cell Activation Syndrome and its Implications with Mental Health and Depression

Epigenetic, Ribosomal, and Immune Dysregulation in Paediatric Acute-Onset Neuropsychiatric Syndrome

Single-Cell RNA Seq in Sydenham Chorea Shows B Cell HLA-DR/DQ Upregulation and Plasma Cell Proteasomal Activation

The Immune/Inflammatory Underpinnings of Neurodevelopmental Disorders and Pediatric Acute-Onset Neuropsychiatric Syndrome: A Scoping Review

Validation of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)-Related Pediatric Treatment Evaluation Checklist (PTEC)

Association of Viral RNAs in the Choroid Plexus with Bipolar Disorder and Schizophrenia and Evidence for the Hepatitis C Virus Involvement in Neuropathology

REM Sleep Atonia in Patients with Pediatric Acute-Onset Neuropsychiatric Syndrome: Implications for Pathophysiology

Pediatric Post-infectious Neuroinflammatory Syndromes Come to the Fore

Immunological Drivers and Potential Novel Drug Targets for Major Psychiatric, Neurodevelopmental, and Neurodegenerative Conditions

Defining Clinical Course of Patients Evaluated for Pediatric Acute-Onset Neuropsychiatric Syndrome: Phenotypic Classification Based on 10 Years of Clinical Data

New-onset OCD and juvenile enthesitis related arthritis after COVID-19 (Three Cases)

Sudden Onset Disordered Eating Behaviors and Appetite Issues in a Local Clinical Cohort of Children With Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)

Acute Onset Neuropsychiatric Conditions in Children and Adolescents following SARS-CoV-2 Infection: A Case Series

Obsessive-Compulsive Disorder Associated with Autoimmunity in Youth: Clinical Course Before and After Rituximab +/− Adjunctive Immunomodulation

Neurological Soft Signs at Presentation in Patients With Pediatric Acute-Onset Neuropsychiatric Syndrome

Pathogenic Variants in Chromatin-Related Genes: Linking Immune Dysregulation to Neuroregression and Acute Neuropsychiatric Disorders

Eight Cases of Pediatric Acute-Onset Neuropsychiatric Syndrome with Inflammatory Bowel Disease: Immunologic Intersections

IL-17 in Serum and Cerebrospinal Fluid of Pediatric Patients with Acute Neuropsychiatric Disorders: Implications for PANDAS and PANS

Naproxen Adjunct to Fluoxetine for Moderate-to-severe Obsessive-compulsive Disorder: A Randomized, Double-blind, Placebo-controlled Trial

IVIG Response in Pediatric Acute-onset Neuropsychiatric Syndrome Correlates with Reduction in Pro-inflammatory Monocytes and Neuropsychiatric Measures

Strep Throat and the Backstory for PANS and PANDAS

Development of Autoimmune Diseases Among Children With Pediatric Acute-Onset Neuropsychiatric Syndrome

Transcobalamin Receptor Antibodies in Autoimmune Vitamin B12 Central Deficiency

Neurofeedback for Obsessive Compulsive Disorder: A Randomized, Double-blind Trial

Anti–SARS-CoV-2 and Autoantibody Profiles in the Cerebrospinal Fluid of 3 Teenaged Patients With COVID-19 and Subacute Neuropsychiatric Symptoms

Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus

Found: The Dial in the Brain that Controls the Immune System

Psychiatry’s Blind Spots: Many mental-health conditions have bodily triggers

Antipsychotic Medications Associated with Increased Length of Hospital Stay in Autoimmune Encephalitis and Multiple Sclerosis: A Retrospective Study

Streptococcal Serology in Children With Stuttering

Postinfectious Inflammation, Autoimmunity, and Obsessive-Compulsive Disorder: Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection, and Pediatric Acute-Onset Neuropsychiatric Disorder

Prospects and Pitfalls of Plasma Complement C4 in Schizophrenia: Building a Better Biomarker

Transcranial Magnetic Stimulation for Developmental Neuropsychiatric Disorders with Inflammation

Clinicopathologic Characteristics of PANDAS in a Young Adult: A Case Report

Evaluation of C4 Gene Copy Number in Pediatric Acute Neuropsychiatric Syndrome

Long COVID Syndrome Presenting as Neuropsychiatric Exacerbations in Autism Spectrum Disorder: Insights for Treatment

Arthritis in Children with Psychiatric Deteriorations: A Case Series

Autoantibodies in Patients with Obsessive-Compulsive Disorder: A Systematic Review

Screen Time and Obsessive-Compulsive Disorder Among Children 9–10 Years Old: A Prospective Cohort Study

Researchers Uncover Mechanisms of Brexanolone and the Role of Inflammation in Post-partum Depression

Evaluation of Brain-Body Health in Individuals with Common Neuropsychiatric Disorders

Autoimmune Encephalitis Criteria in Clinical Practice

Immunosuppressants Linked to Severe Reactions in People with Common Genetic Profile

Neuroimmune Cell Signaling in Covid-19

Further Understanding of Neuro-Immune Interactions in Allergy: Implications in Pathophysiology and Role in Disease Progression

Tractography-based Versus Anatomical Landmark-Based Targeting in Valic Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

Elevated Biomarkers Associated with PASC Phenotype

In Vivo Detection of Macromolecule Free Radicals in Mouse Sepsis-Associated Encephalopathy Using a New MRI and Immunospin Trapping Strategy

How the Brain’s Housekeeper Malfunctions During Bacterial Meningitis

A New Lyme Disease Test in Development May Help Improve Treatment

Pneumolysin Boosts the Neuroinflammatory Response to Streptococcus Pneumoniae Through Enhanced Endocytosis

Research Round-up: Depression

Cytokine Dynamics and Targeted Immunotherapies in Autoimmune Encephalitis

Cytokine Profile of Pediatric Patients with Obsessive-Compulsive and/or Movement Disorder Symptoms: A Review

Study Shows Viruses Can Kill Gut Bacteria of Crohn’s, Bowel Disease

Vitamin D supplements may help reduce chronic inflammation, study finds

Vitamin D Supplements’ Link to Depression Investigated in New Meta-Analysis

Epidural Nerve Block with Lidocaine Leads to Clearance of Psoriatic Skin Lesions

Biallelic PAX5 Mutations Cause Hypogammaglobulinemia, Sensorimotor Deficits, and Autism Spectrum Disorder

Neuroinflammation Microstructural Evidence: Psychological Symptoms & Pain in Fibromyalgia

Reflecting on the Immunopathology of Arthritis Associated with Inflammatory Bowel Disease: What Do We Know and What Should We Know?

Association of Pediatric Acute-Onset Neuropsychiatric Syndrome with Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging

Antibodies May Provide a New Treatment for OCD

Schizophrenia is Associated With an Aberrant Immune Response to Epstein-Barr Virus

Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression

Association of Exposure to Infections in Childhood With Risk of Eating Disorders in Adolescent Girls

Montelukast and Neuropsychiatric Events in Children with Asthma: A Nested Case-control Study

Immunoglobulin A Dysgammaglobulinemia Is Associated with Pediatric-Onset Obsessive-Compulsive Disorder

Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia

Psychotic Symptoms in Youth with Pediatric Acute-onset Neuropsychiatric Syndrome (Pans) May Reflect Syndrome Severity and Heterogeneity

Microbes and Monoamines: Potential Neuropsychiatric Consequences of Dysbiosis

Recurrent Group A Streptococcus Tonsillitis is an Immunosusceptibility Disease Involving Antibody Deficiency and Aberrant ᵗᶠH Cells

The Gut Microbiome from Patients with Schizophrenia Modulates the Glutamate-Glutamine-GABA Cycle and Schizophrenia-Relevant Behaviors in Mice

Maternal Thyroid Autoimmunity Associated with Acute‐onset Neuropsychiatric Disorders and Global Regression in Offspring

Rapamycin Alleviates Inflammation by Up-Regulating Tgf-Β/Smad Signaling in a Mouse Model of Autoimmune Encephalomyelitis

Psychotic Symptoms in Youth with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) May Reflect Syndrome Severity and Heterogeneity

The Burden of Caring for a Child or Adolescent With Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): An Observational Longitudinal Study

GABA-Modulating Bacteria of the Human Gut Microbiota

Aspirin Ameliorates Experimental Autoimmune Encephalomyelitis Through Interleukin-11–mediated Protection of Regulatory T Cells

Herpes Simplex Virus 1 Infection and Valacyclovir Treatment in Schizophrenia: Results from the Vista Study

Mast Cells at the Crossroads of Microbiota and IBD

Neuropsychiatric Lupus with Antibody-mediated Striatal Encephalitis

An Atypical Presentation of Pediatric Acute Neuropsychiatric Syndrome Responding to Plasmapheresis Treatment

Neuroimmune Disorders of the Central Nervous System in Children in the Molecular Era

Anti-neuronal and Anti-microbial Immunity Link CaMKII and Autism Spectrum Disorder with Pediatric Acute-onset Neuropsychiatric Syndrome

Advances in Biomarker-guided Therapy for Pediatric- and Adult-onset Neuroinflammatory Disorders: Targeting Chemokines/Cytokines

A Clinical Approach to New-Onset Psychosis Associated with Immune Dysregulation: The Concept of Autoimmune Psychosis

Successful Treatment of Postural Orthostatic Tachycardia and Mast Cell Activation Syndromes Using Naltrexone, Immunoglobulin and Antibiotic Treatment

Autoimmune Encephalitis with GABAₐ Receptor Antibodies in a 10-year-old Girl

Effect of Early and Prophylactic Nonsteroidal Anti-Inflammatory Drugs on Flare Duration in PANS: An Observational Study of Patients Followed by an Academic Community-Based PANS Clinic

Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part III—Treatment and Prevention of Infections

Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part II—Use of Immunomodulatory Therapies

Neurotransmitters: the Critical Modulators Regulating Gut-Brain Axis

Effects of Bumetanide on Neurobehavioral Function in Children and Adolescents with Autism Spectrum Disorders

Autoimmune Encephalopathies

The Dopaminergic System in Autoimmune Diseases

Anti-N-methyl-D-aspartate (NMDA) Receptor Encephalitis: an Unusual Cause of Autistic Regression in a Toddler

IL-1β And TNF-α Induce Neurotoxicity Through Glutamate Production: a Potential Role for Neuronal Glutaminase

Frequency of Neuro-Psychiatric Dysfunction in Anti-SSA/SSB Exposed Children With and Without Neonatal Lupus